Trimethoprim: laboratory and clinical studies

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Trimethoprim: laboratory and clinical studies.

Trimethoprim is a synthetic compound which arrests the step in bacterial purine synthesis immediately succeeding that interfered with by sulphonamides. Acting alone it inhibits the growth of a wide range of bacteria in generally much lower concentrations than sulphonamides. Its action with a sulphonamide is strongly synergic and bactericidal.Studies are described of suitable cultural conditions...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1968

ISSN: 0021-9746

DOI: 10.1136/jcp.21.2.202